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Carpal Tunnel Syndrome

Carpal Tunnel Syndrome on one page: when to suspect it, assessment, management, red flags, referral criteria and GP tips.

Written and reviewed by practising UK GPs, overseen by our Clinical Advisory Officer. Last reviewed 1 Oct 2025.

πŸ” When to Suspect

Numbness, tingling, or pain in the thumb, index, middle, and radial half of the ring finger, often worse at night and relieved by shaking the hand

From the full topic in The Ocean Library: Carpal Tunnel Syndrome

🧭 When to suspect

Carpal tunnel syndrome (CTS) is compression of the median nerve as it passes through the carpal tunnel at the wrist, and it is the commonest entrapment neuropathy seen in general practice. Suspect it in any patient describing numbness, tingling or pain in the thumb, index, middle and radial half of the ring finger – the little finger is characteristically spared, because it is supplied by the ulnar nerve, and this single point is one of the most useful discriminators at the bedside.

The hallmark is nocturnal paraesthesia that wakes the patient from sleep and is relieved by shaking the hand (the β€œflick sign”). Symptoms are bilateral in over half of cases, and pain may radiate proximally up the forearm. As compression advances, intermittent tingling gives way to constant numbness and, eventually, weakness and wasting of the thumb muscles.

The diagnosis is made clinically from this history. The key primary-care task is to grade severity, screen selectively for treatable associations, and decide between a conservative pathway and surgical referral – bearing in mind that up to a third of cases settle spontaneously.

Severity Typical features Action
Mild Intermittent tingling/pain; symptoms come and go; no sensory loss or weakness Conservative – nocturnal splint, activity modification
Moderate More frequent or persistent symptoms, some by day; possible mild sensory blunting; no significant weakness Conservative Β± corticosteroid injection; refer if no benefit by ~3 months
Severe Constant numbness, definite sensory loss, or thumb (thenar) weakness/wasting Refer for surgical decompression – do not delay

Source: BSSH Β· BJGP


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