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Vulval Conditions

Reviewed and updated by practising UK GPs, overseen by our Clinical Advisory Officer.

🧭 When to suspect

Suspect a vulval dermatosis in any woman with persistent vulval itch, soreness, pain or burning – particularly when empirical treatment for "thrush" has repeatedly failed.

• As the British Association of Dermatologists puts it, "not all that itches is thrush".

• Symptoms are often longstanding and have a real impact on sleep, sexual function and psychological wellbeing.

• The vulva is frequently treated without ever being examined.

Examine the vulva and recognise the pattern, and never miss a malignancy.

• Most inflammatory dermatoses respond well to a soap substitute, an emollient and an appropriately-potent topical steroid.

• The diagnosis must be made first, and lichen sclerosus must not be left untreated.

Dermatosis Tell-tale clinical clues
Lichen sclerosus

• Porcelain-white, crinkled ("cigarette-paper") atrophic plaques

• Figure-of-eight vulval/perianal pattern

• Architectural loss (resorbed labia minora, buried clitoris)

• Spares the vagina

Lichen planus (erosive)

• Glazed red erosions at the vestibule/introitus

• White lacy Wickham striae

• Vaginal and oral involvement

• Scarring and adhesions

Eczema or contact dermatitis

• Erythema, scaling, fissuring and itch

• Irritant (soaps, wipes, incontinence) or allergic (fragrance, medicaments)

Psoriasis (flexural)

• Well-demarcated red plaques, often non-scaly in the flexure

• Clues at scalp, nails, elbows and natal cleft

Lichen simplex chronicus

• Thickened, leathery, lichenified skin from a chronic itch–scratch cycle

• Often unilateral

⚠️ Common pitfall

• Issuing repeated antifungals for "recurrent thrush" over months or years without ever inspecting the vulva.

• Candidiasis is the single commonest misdiagnosis given in place of lichen sclerosus, and it is the main reason LS is recognised late – after avoidable scarring has occurred.

• If symptoms recur or antifungals do not work, examine the vulva and look for a dermatosis.

Persistent vulval itch,soreness or burning•'not all that itches is thrush'•repeated failed antifungals: examine thevulva•candidiasis is the commonestmisdiagnosis given in place of lichensclerosusRed flag on inspection?•unexplained lump, persistent ulcer orunexplained bleeding•indurated, fixed or thickened red, whiteor pigmented patchSuspected cancer pathwayreferral•new or changing lesion in known lichensclerosus: urgent review•failure to respond to an adequatepotent/ultrapotent steroid•course is a red flag in its own right:refer for biopsyFoundation for everydermatosis•stop all soaps, washes, wipes andfragranced products•soap substitute + greasy emollient;barrier ointment•ointments rather than creams on vulvalskin•under-treatment is the real risk, notthe steroidVagina (or mouth) involved?the single most useful discriminator:lichen sclerosus spares the vagina,erosive lichen planus does notErosive lichen planus: refer•glazed red erosions at the vestibule;white lacy Wickham striae•desquamative vaginitis, adhesions,introital stenosis•ultrapotent topical steroid, specialist-ledPorcelain-white crinkledplaques, or architecturalloss?figure-of-eight vulval/perianal pattern;resorbed labia minora, buried clitoris;atrophic 'cigarette-paper' skinLichen sclerosus: treatactively, for life•clobetasol propionate 0.05% ointment(Dermovate): once daily•1 month, alternate days 1 month, twiceweekly 1 month, maintain•annual review; ~4-5% lifetime vulval SCCrisk: self-examination•second-line (specialist): tacrolimus0.1% ointment (Protopic)Eczema or contact dermatitis•remove the irritant or allergen; patchtest if allergic suspected•mild: hydrocortisone 1%; moderate:clobetasone butyrate 0.05% (Eumovate) orbetamethasone valerate 0.025%(Betnovate-RD)•lichenified: mometasone furoate 0.1%(Elocon) or BetnovatePsoriasis (flexural)•well-demarcated, often non-scaly; cluesat scalp, nails, elbows•mild-moderate steroid in short coursesto limit atrophy•avoid vitamin D analogues, dithranol ortar on genital skinLichen simplex chronicus•thickened leathery skin from the itch-scratch cycle•break it: clobetasol propionate 0.05%(Dermovate), defined course•sedating antihistamine (hydroxyzine) orlow-dose amitriptyline•at night for nocturnal scratchingYESNOYESNOYESerythema, scaling, fissuringdemarcated flexural plaqueslichenified, worse at nightNot all that itches is thrushOcean 🌊GPAtlas Ocean 🌊

Source: British Association of Dermatologists · DermNet


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