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🌊 The Ocean Library · GP clinical topic

Scarlet Fever

Written and reviewed by practising UK GPs, overseen by our Clinical Advisory Officer.

🧭 When to suspect

Suspect scarlet fever in any child – or, less commonly, an adult – presenting with the classic triad of fever, severe sore throat (streptococcal tonsillitis), and a characteristic fine, sandpaper-like rash. It is caused by toxin-producing strains of Streptococcus pyogenes (group A streptococcus, GAS) – the same organism responsible for strep throat and impetigo – in people susceptible to the erythrogenic exotoxin.

Scarlet fever is predominantly a disease of early childhood: around 90% of cases occur in children under 10, most commonly between the ages of 2 and 8 years (peak age 4). Most people over 10 have developed immunity to the toxin. England currently sees roughly 15,000–30,000 cases a year, with notifications rising markedly since 2014. It is a statutory notifiable disease, the diagnosis is clinical, and treatment should be started on clinical suspicion rather than waiting for swab confirmation.

Phase Typical features
Incubation (1–7 days; usually 2–5) Asymptomatic; the person may already be infectious.
Prodrome (first 12–48 h) Abrupt fever, sore throat with tonsillitis, headache, malaise, and often nausea or vomiting. Cough and coryza are usually absent.
Rash phase (12–48 h after onset) Fine, blanching, sandpaper rash starting on the neck, chest and abdomen and spreading to the limbs (sparing palms and soles); flushed cheeks with circumoral pallor; strawberry tongue; Pastia's lines in the skin folds. The rash spares the face.
Convalescence (after ~1 week) Desquamation – peeling of the skin, classically of the fingertips, toes and groin – as the rash fades.

Raise suspicion particularly during the winter and spring peak and where there is a known local outbreak or close contact with a confirmed case of scarlet fever or streptococcal sore throat. Scarlatina (a milder form) may present with the rash and few other symptoms.

Source: NICE NG84 · UKHSA


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