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๐ŸŒŠ The Ocean Library ยท GP clinical topic

Myocardial Infarction (MI) - Secondary Prevention

Reviewed and updated by practising UK GPs, overseen by our Clinical Advisory Officer.

๐Ÿงญ When to review โ€“ post-MI secondary prevention

This article covers the longer-term primary-care management of everyone discharged after a myocardial infarction (MI) โ€“ whether ST-elevation MI (STEMI), non-ST-elevation MI (NSTEMI) or unstable angina.

The goal is secondary prevention:

โ€ข Reducing the risk of a further acute coronary syndrome (ACS).

โ€ข Managing complications such as heart failure or arrhythmia.

โ€ข Restoring quality of life.

Make sure the four core secondary-prevention drugs are prescribed, tolerated and actually taken, and keep the person engaged with cardiac rehabilitation and risk-factor control.

โ€ข No single agent delivers the benefit on its own โ€“ it is the package that lowers mortality.

โ€ข The main thing that determines whether it works is adherence.

Conduct a structured review at least annually (sooner after any dose change). Two things should always be to hand: the discharge summary (type of MI, stents, latest left ventricular ejection fraction) and an up-to-date medication list.

Review domain What to assess and optimise
Medicines & adherence

โ€ข Confirm the four core drugs are prescribed, tolerated and taken

โ€ข Ask about side effects

โ€ข Assess bleeding risk

โ€ข Check how long dual antiplatelet therapy should continue

Blood pressure Optimise control as part of overall cardiovascular risk reduction.
Lipids

โ€ข Full lipid profile

โ€ข Low-density lipoprotein (LDL) or non-HDL cholesterol to target on a high-intensity statin

Glycaemia HbA1c at least annually โ€“ risk of type 2 diabetes is increased after ACS.
Renal function & electrolytes U&E before and after any ACE inhibitor, ARB or aldosterone-antagonist change, then at least annually.
Left ventricular (LV) function & symptoms

โ€ข Confirm the latest left ventricular ejection fraction

โ€ข Reassess if heart-failure status changes (it drives beta-blocker, aldosterone-antagonist and device decisions)

Lifestyle Smoking, diet, physical activity, weight and alcohol.
Mood Screen for depression and anxiety, which are common and worsen outcomes.
Cardiac rehabilitation Confirm whether referred, attending or completed.
Vaccination Annual influenza and a one-off pneumococcal vaccine (chronic heart disease is an at-risk group).

Source: NICE NG185 ยท NICE NG238


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