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Hypertension (HTN)

Reviewed and updated by practising UK GPs, overseen by our Clinical Advisory Officer. Last updated 20 Feb 2026.

🧭 When to suspect

Hypertension is usually asymptomatic – the “silent killer”. It is most often found through opportunistic screening or as an incidental clinic reading, rather than because the patient feels unwell.

Suspect it when:

• A clinic blood pressure (BP) is ≥ 140/90 mmHg, or

• There is evidence of hypertension-mediated organ damage (left ventricular hypertrophy, chronic kidney disease, retinopathy or raised urine albumin:creatinine ratio).

A single high clinic reading is not a diagnosis.

• A discrepancy of more than 20/10 mmHg between clinic and out-of-office readings (the white-coat effect) is common.

• Confirm the diagnosis with ambulatory BP monitoring (ABPM) – or home BP monitoring (HBPM) if ABPM is unsuitable or not tolerated – unless the clinic BP is in the severe range.

• A clinic BP in the severe range (≥ 180/120 mmHg) warrants more urgent action.

• Adults with a normal BP should be screened at least every 5 years.

Category Clinic BP ABPM/HBPM average
Normal or not diagnosed < 140/90 mmHg –
Stage 1 140/90 – 159/99 mmHg 135/85 – 149/94 mmHg
Stage 2 ≥ 160/100 (and < 180/120) mmHg ≥ 150/95 mmHg
Stage 3 (severe) Systolic ≥ 180 or diastolic ≥ 120 mmHg Confirm urgently or same-day review if indicated

Raise suspicion of a secondary cause in anyone aged under 40, in resistant hypertension, or where the history points to it:

• Paroxysmal headache, palpitations, pallor and sweating (phaeochromocytoma).

• Muscle weakness or hypokalaemia (primary hyperaldosteronism or Conn’s).

• Snoring and daytime somnolence (obstructive sleep apnoea).

• Renal disease.

Always review BP-raising agents – NSAIDs, corticosteroids, combined oral contraceptives, venlafaxine, decongestants and liquorice.

Clinic BP ≥ 140/90 mmHg•a single high clinic reading is not adiagnosis•measure both arms; use the higher ifdifference > 15 mmHgClinic BP ≥ 180/120 mmHg?Same-day specialist assessment•retinal haemorrhage or papilloedema(accelerated hypertension)•new confusion, chest pain, heart failureor AKI•labile BP with headache, palpitations,pallor, sweating: phaeochromocytomaSevere without symptoms•assess for organ damage the same day•if present, start treatment withoutwaiting for ABPM/HBPMConfirm with ABPM (or HBPM ifunsuitable)white-coat effect: clinic minus out-of-office > 20/10 mmHgStagingClinic < 140/90 mmHgnormal or not diagnosed; screen atleast every 5 yearsClinic 140/90-159/99;ABPM/HBPM 135/85-149/94stage 1: treat by QRISK3 ≥ 10%,organ damage, CVD, renal disease,diabetesClinic ≥ 160/100 (<180/120); ABPM/HBPM ≥150/95stage 2: offer drug treatment at anyageSystolic ≥ 180 ordiastolic ≥ 120stage 3 (severe): confirm urgently,same-day review if indicatedU&E after ACEi/ARB startaccept creatinine rise ≤ 30% or eGFRfall ≤ 25%Lifestyle advice for everyone•< 6 g salt/day, < 14 units/week alcohol•consider a secondary cause if aged < 40or resistantYES, with symptoms or organ damageYES, no symptomsNOStaging and the severe-range exceptionsOcean 🌊GPAtlas Ocean 🌊

Source: NICE NG136


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