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๐ŸŒŠ The Ocean Library ยท GP clinical topic

Hypertension (HTN) in Pregnancy

Written and reviewed by practising UK GPs, overseen by our Clinical Advisory Officer.

๐Ÿงญ When to suspect

Hypertension complicates up to 1 in 10 pregnancies and remains a leading cause of maternal and perinatal morbidity. Define hypertension in pregnancy as a sustained blood pressure (BP) โ‰ฅ 140/90 mmHg; severe hypertension is โ‰ฅ 160/110 mmHg. Three patterns matter in primary care: chronic hypertension (present before pregnancy or before 20 weeks, or already on antihypertensives), gestational hypertension (new after 20 weeks, without significant proteinuria), and pre-eclampsia (new hypertension after 20 weeks with proteinuria and/or maternal organ dysfunction).

The pivotal shift to remember is that pre-eclampsia no longer requires proteinuria. New hypertension after 20 weeks plus maternal organ dysfunction (kidney, liver, neurological or haematological) or fetal growth restriction is sufficient to diagnose it. A clean urine dipstick therefore never excludes pre-eclampsia.

The primary-care role is threefold: risk-stratify early and offer aspirin prophylaxis from 12 weeks to those who qualify; recognise and urgently refer new hypertension or pre-eclampsia symptoms after 20 weeks; and provide safe pharmacological management and postnatal follow-up. New hypertension after 20 weeks is assessed in secondary care (maternity), not in primary care alone.

Pattern Definition / timing Key primary-care action
Chronic hypertension BP โ‰ฅ 140/90 mmHg before pregnancy or before 20 weeks (or already on treatment) Pre-conception/early review: stop unsafe drugs, switch to a pregnancy-safe agent, start aspirin from 12 weeks, refer to specialist
Gestational hypertension New BP โ‰ฅ 140/90 mmHg after 20 weeks, without significant proteinuria Same-day maternity (secondary-care) assessment; watch closely for evolution into pre-eclampsia
Pre-eclampsia New BP โ‰ฅ 140/90 mmHg after 20 weeks plus proteinuria and/or maternal organ dysfunction (renal, hepatic, neurological, haematological) or fetal growth restriction Urgent maternity assessment / admission โ€“ the diagnosis that must never be missed
Severe hypertension (any pattern) BP โ‰ฅ 160/110 mmHg Emergency admission for rapid control, whatever the underlying pattern

Source: NICE NG133


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