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🌊 The Ocean Library · GP clinical topic

Haematospermia

Reviewed and updated by practising UK GPs, overseen by our Clinical Advisory Officer. Last updated 5 Oct 2026.

🧭 When to suspect

Haematospermia is the presence of blood in the ejaculate (semen).

• It is usually a painless, isolated, benign and self-limiting symptom.

• Peak incidence is between the ages of 30 and 40.

• In around half of cases no cause is found (idiopathic).

• The patient is often far more frightened than the symptom warrants, commonly fearing cancer or a sexually transmitted infection (STI).

• Calm, structured assessment and clear reassurance are central to good care.

There are two clinical tasks:

• Identify and treat the minority with a treatable or serious cause.

• Reassure the majority robustly.

Risk is driven by age and persistence:

• A man under 40 with a single painless episode and a normal examination is very low risk.

• New-onset haematospermia over 40, or persistent or recurrent symptoms at any age, carries a higher chance of underlying pathology – most importantly prostate cancer.

Cause category Examples
Idiopathic

• No cause found in around half of men, especially younger patients

• Benign and self-limiting

Iatrogenic

• Recent prostate biopsy (very common and expected for weeks)

• Also catheterisation and post-vasectomy

Infection/inflammation

• Prostatitis, urethritis, epididymo-orchitis

• STIs (chlamydia, gonorrhoea)

• Urinary tract infection (UTI)

• The commonest identifiable cause under 40

Trauma Perineal or testicular injury, vigorous cycling, instrumentation.
Obstruction/cysts/stones Seminal-vesicle or prostatic cysts, calculi, ejaculatory-duct obstruction – typically cause persistent or recurrent bleeding.
Vascular/systemic

• Severe uncontrolled hypertension

• Bleeding disorders

• Anticoagulant or antiplatelet drugs

Neoplastic (uncommon)

• Prostate cancer (mainly over 40)

• Rarely seminal-vesicle, testicular, bladder or urethral tumours

• Benign prostatic hyperplasia (BPH)

🧠 Clinical pearl

• Recent prostate biopsy is one of the most common causes of all.

• Haematospermia is expected for up to several weeks after transrectal (TRUS) or transperineal prostate biopsy, and after some other urological procedures.

• Ask about recent procedures before embarking on any work-up – it spares the patient unnecessary investigation.

• Immediate reassurance is usually all that is required.

Source: NICE NG12 · BAUS


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