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🌊 The Ocean Library · GP clinical topic

Community-Acquired Pneumonia (CAP)

Written and reviewed by practising UK GPs, overseen by our Clinical Advisory Officer.

🧭 When to suspect

Community-acquired pneumonia (CAP) is an acute lower respiratory tract infection acquired outside hospital (or within 48 hours of admission), in which infection inflames the lung tissue itself. In primary care the diagnosis is clinical: suspect CAP in a patient with an acute cough plus at least one other lower respiratory tract symptom – breathlessness, pleuritic chest pain, sputum or wheeze – together with new focal chest signs on examination. Systemic features such as fever, sweats, rigors or malaise raise the probability further.

A chest X-ray is not needed to make the diagnosis in the community. Once CAP is diagnosed clinically, two decisions dominate: stratify severity using the CRB65 score alongside clinical judgement, and decide the safest place of care. Most patients are managed at home, but the 2025 NICE update widened the middle ground – a virtual ward, same-day emergency care (SDEC) or hospital-at-home service now sit between β€œhome” and β€œadmit”.

The CRB65 score gives 1 point each for Confusion (new disorientation, or abbreviated Mental Test score ≀ 8), Respiratory rate β‰₯ 30/min, low Blood pressure (systolic < 90 mmHg or diastolic ≀ 60 mmHg) and age β‰₯ 65. It estimates 30-day mortality risk and guides – but never replaces – the place-of-care decision. (In hospital, the CURB65 score adds a point for Urea > 7 mmol/L.)

CRB65 score 30-day mortality risk Severity Suggested place of care
0 < 1% (low) Low Primary care-led, with safety-netting
1 1–10% (intermediate) Low–moderate Primary care-led with safety-netting, or refer to virtual ward / SDEC / hospital-at-home / hospital
2 1–10% (intermediate) Moderate Consider referral to hospital (or virtual ward / SDEC / hospital-at-home)
3–4 > 10% (high) High Refer to hospital; consider critical care

Refer regardless of the score if there are features of sepsis or cardiorespiratory failure, or if the patient cannot take oral medicines.

Source: NICE NG250


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