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🌊 The Ocean Library · GP clinical topic

Blepharitis

Reviewed and updated by practising UK GPs, overseen by our Clinical Advisory Officer.

🧭 When to suspect

Blepharitis is chronic inflammation of the eyelid margins and one of the commonest reasons a patient brings an irritable eye to primary care – it accounts for at least 5% of eye presentations.

Suspect it in an adult (onset is typically in the fourth or fifth decade) with:

β€’ Bilateral, persistent sore, gritty, itchy or burning eyes that are characteristically worse on waking

β€’ Eyelids that stick together

β€’ Crusting or flakes at the lash base

Symptoms relapse and remit, and are often disproportionate to the modest signs found on examination.

Raise suspicion particularly where there is a background of:

β€’ Seborrhoeic dermatitis

β€’ Acne rosacea

β€’ Eczema

β€’ Psoriasis

β€’ Dry eye disease

Two anatomical patterns exist and frequently overlap:

β€’ Anterior blepharitis affects the lash base and is either staphylococcal or seborrhoeic

β€’ Posterior blepharitis reflects meibomian gland dysfunction (MGD) and is the commonest form

The clinical skill in primary care is to:

β€’ Recognise the pattern

β€’ Treat the right way (lid hygiene first, antibiotics only where they add value)

β€’ Never dismiss truly unilateral or treatment-resistant lid disease, which can hide a tumour

Type Site Typical features
Anterior – staphylococcal Base of the lashes

β€’ Hard scales and collarettes at the lash base, lid-margin telangiectasia

β€’ Lash distortion or loss

β€’ More common in women

Anterior – seborrhoeic Base of the lashes

β€’ Greasy, soft scales with lashes stuck together

β€’ Less inflammation

β€’ Signs of seborrhoeic dermatitis on scalp/brows

Posterior (MGD) – commonest Meibomian gland orifices

β€’ Capped, oily or foamy gland orifices, frothy/unstable tear film, lid-margin telangiectasia

β€’ Strongly linked to rosacea

Source: College of Optometrists Β· DermNet


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