๐งญ When to suspect
Recurrent aphthous stomatitis (RAS), or aphthous ulcers, is the most common disease of the oral mucosa, affecting up to 1 in 4 people. It usually begins in childhood or adolescence and tends to settle with age.
The hallmark is recurrent crops of painful, round or oval ulcers:
โข With a yellow-grey floor and an erythematous halo
โข Appearing on non-keratinised (movable) mucosa โ buccal and labial mucosa, floor of mouth, and the ventral/lateral tongue
โข They characteristically spare the hard palate, attached gingiva and dorsum of the tongue
Diagnosis is clinical, and the great majority are benign and self-limiting.
There are two jobs in primary care:
โข The first is to recognise the benign recurrent pattern and treat symptomatically.
โข The second โ the one that matters most โ is to never dismiss a single, persistent ulcer: an unexplained ulcer lasting more than 3 weeks needs a suspected cancer pathway referral.
Suspect a secondary cause when ulcers:
โข Begin in adulthood
โข Are unusually severe or frequent
โข Come with systemic features
Think of:
โข Haematinic deficiency
โข Coeliac disease
โข Inflammatory bowel disease
โข Behรงet's disease
| Subtype | Typical appearance | Course |
|---|---|---|
| Minor (most common) | Crops of small ulcers, each < 10 mm, on non-keratinised mucosa | Heal in 10โ14 days, no scarring |
| Major | One to three larger ulcers, > 10 mm, any site including soft palate/fauces | Heal over weeks, may scar |
| Herpetiform | โข 10โ50 pinpoint ulcers that may coalesce โข Not caused by herpes virus |
Heal in 10โ14 days |
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